IVF Treatment Timeline: Your Day-by-Day Journey in Istanbul
One of the first questions every international patient asks me is: “How long do I need to stay in Istanbul?” After 30+ years of guiding families through IVF, I know that a clear timeline removes half the anxiety. Below is the complete day-by-day map of your journey.
Your Complete IVF Timeline
Pre-Arrival: Remote Consultation via WhatsApp (Week −4 to −2)
Duration: Ongoing WhatsApp conversation · Location: From home
Before you travel, we review your medical history, hormone levels (AMH, FSH, E2), and any previous treatment records through WhatsApp. You share your test results, ultrasound images, and questions directly via chat — and Dr. Aksoy’s team responds promptly. Your personal coordinator — Berna (French), Sameh (Arabic), or our English team — will be your single point of contact throughout the entire journey.
What you receive: A personalized protocol, medication prescription (purchase in your own country), and a tentative travel date based on your cycle — all coordinated through WhatsApp.
Days 1–3: Medication Start (At Home)
Duration: 3 days · Location: Home country
You begin daily gonadotropin injections (stimulation medication) at home. Our team monitors you remotely — you send us blood work results and, if possible, a local ultrasound scan. This means fewer days away from family and work.
Day 4: Arrival in Istanbul
Duration: Travel day · Location: Istanbul
You fly to Istanbul. Our team meets you at the airport and transfers you to your hotel (5–15 minutes from the clinic). Settle in and rest. If you arrive by early afternoon, we schedule your first in-clinic ultrasound the same day.
Days 5–10: Monitoring & Stimulation
Duration: 5–6 days · Location: Clinic visits every 1–2 days
You continue your stimulation injections. Every 1–2 days you visit the clinic for a transvaginal ultrasound and blood test. Dr. Aksoy personally reviews each scan and adjusts medication doses to optimize follicle growth. Between appointments, Istanbul is yours to explore.
Typical schedule: Morning clinic visit (30–45 min) → free for the rest of the day.
Day 10–11: Trigger Shot
Duration: 1 injection, precise timing · Location: Hotel or clinic
When your follicles reach the ideal size (17–22 mm), we administer the “trigger shot” (hCG or GnRH agonist). This injection is timed exactly 36 hours before egg retrieval. We will tell you the exact hour to take it.
Day 12: Egg Retrieval (OPU)
Duration: ~20 minutes under sedation · Location: Operating room
The egg retrieval is performed under light sedation — you sleep comfortably and wake up without pain. Dr. Aksoy uses ultrasound-guided aspiration to collect your eggs. You rest at the clinic for 1–2 hours and return to your hotel the same day.
Same day: Your partner provides a sperm sample (or we thaw a frozen sample). The embryologist begins fertilization via ICSI that afternoon.
Days 13–16: Embryo Development
Duration: 3–5 days · Location: Laboratory (you rest and explore)
Your embryos develop in our state-of-the-art incubators. The embryology team sends you daily updates — how many fertilized, how they are dividing, and which are developing into blastocysts. These are free days for you to enjoy Istanbul, attend your follow-up appointment, and relax.
Day 15–17: Embryo Transfer
Duration: ~10 minutes, no anesthesia · Location: Clinic
The best-quality embryo(s) are transferred to your uterus using a thin, soft catheter — guided by ultrasound. The procedure is painless (no sedation needed) and takes about 10 minutes. Dr. Aksoy will show you the embryo on screen before transfer.
After transfer: Rest at the clinic for 30 minutes, then return to your hotel. Light activity is fine — there is no need for strict bed rest.
Day 17–18: Return Home
Duration: Travel day · Location: Airport
You can fly home 24–48 hours after embryo transfer. Air travel does not affect implantation. We provide you with a complete medication schedule and written instructions to share with your local doctor.
Day 27–29: Pregnancy Test (Beta-hCG)
Duration: Blood test · Location: Your home country
Approximately 12 days after transfer, you take a blood pregnancy test (beta-hCG) at a local laboratory. You share the result with us, and Dr. Aksoy calls you personally to discuss the next steps. If positive, we coordinate your follow-up with your local gynecologist.
Frequently Asked Questions
How long do I need to stay in Istanbul?
Most patients stay 12–16 days from arrival to departure. Starting stimulation at home can reduce this to 10–12 days.
Can I start medications at home?
Yes. We send your prescription so you can purchase medications locally. The first 2–4 days of injections can be done at home with remote monitoring.
When can I fly after embryo transfer?
You may fly 24–48 hours after transfer. Multiple studies confirm that air travel has no negative impact on implantation rates.
Will I know the results before leaving Istanbul?
Not typically. The pregnancy blood test is taken 12 days after transfer, which means most patients receive their result at home. We remain in close contact throughout.
What if I need a frozen embryo transfer (FET)?
A FET cycle is shorter — typically 5–7 days in Istanbul. There is no stimulation phase or egg retrieval; we prepare your uterine lining and transfer a previously frozen embryo.
How do I get my medications?
Dr. Aksoy provides a prescription after your video consultation. You purchase the medications at a pharmacy in your country. In many European countries, these are partially covered by insurance.